Oxidative stress plays a central role in most chronic liver diseases and, in particular, in metabolic dysfunction-associated fatty liver disease (MAFLD), the new definition of an old condition known as non-alcoholic fatty liver disease (NAFLD).The mechanisms leading to hepatocellular fat accumulation in genetically predisposed individuals who adopt
A commercial territory design problem with compactness maximization criterion subject to territory balancing and connectivity is addressed.Four new heuristics based on Greedy Randomized Adaptive Search Procedures within a location-allocation scheme for this NP-hard combinatorial optimization problem are proposed.The first three (named GRLH1, GRLH2,
We consider a set of hard point particles distributed uniformly with a specified density on the positive ETi 250 Parts half-line and all initially at rest.The particle masses alternate between two values, $m$ and $M$.The particles interact via collisions that conserve energy and momentum.We study the cascade of activity that results when the left-m
In recent years due to a significant increase in the interest of the Russian film audience to the patriotism topic and the emergence of a social demand for Patriotic cinema, there has been a significant growth in the film distribution share that affects the historical and social aspects of patriotism.The reflection of the idea of patriotism in the
Staphylococcus spp.bacteria are the most frequently involved agents in canine cutaneous infections.Treatment of these infections is based on antibiotic therapy, that often is not effective because of the antibiotic-resistance of the bacterial strains.Cutaneous staphylococcal infections are often complicated by Malassezia yeasts, that may be resista